• Member of Polish Chemical Society
• Member of the Forensic and Toxicological Analysis Team within the Analytical Chemistry Committee of the Polish Academy of Sciences
• Member of the Scientific Council of the Chemical Sciences discipline

Our research is mainly focusing on the modification of selected groups of alkaloids and study their structure–activity relationships.

Antioxidant compounds play an important role as a health protecting factor by reducing the risk of chronic diseases induced by ROS, including cancer and heart disease. Therefore, the caffeine and gramine molecules remain in the focus of our interest for further modification in the hope of increasing their antioxidant and cytoprotective properties. The antioxidant and cytoprotective properties of the new derivatives are analyzed using standard chemical tests and an in vitro cell system using human erythrocytes as model cells in the study of the biological activity of the compounds. Research on human erythrocytes is conducted in cooperation with the Faculty of Biology of the Adam Mickiewicz University.

1. R. Wawrzyniak, B. Jasiewicz, Straightforward and rapid determination of acrylamide in coffee beans by means of HS-SPME/GC-MS. Food Chemistry 301 (2019) 125264
2. R. Wawrzyniak, W. Wasiak, B. Jasiewicz, A. Bączkiewicz, K. Buczkowska, Chemical Fingerprinting of Cryptic Species and Genetic Lineages of Aneura pinguis (L.) Dumort. (Marchantiophyta, Metzgeriidae). Molecules 26 (2021) 1180
3. B. Jasiewicz, W. Kozanecka‑Okupnik, M. Przygodzki, B. Warżajtis, U. Rychlewska, T. Pospieszny, L. Mrówczyńska, Synthesis, antioxidant and cytoprotective activity evaluation of C‑3 substituted indole derivatives. Scientific reports 11 (2021) 15425
4. W. Kozanecka-Okupnik, A. Sierakowska, N. Berdzik, I. Kowalczyk, L. Mrówczyńska, B.Jasiewicz, New triazole-bearing gramie derivatives–synthesis, structural analysis and protective effect against oxidative haemolysis. Natural Product Research 36 (2022) 3413
5. D. Nowak, K. Babijczuk, L.O.I. Jaya, R.A. Bachorz, L. Mrówczyńska, B. Jasiewicz, M. Hoffmann, Artificial Intelligence in Decrypting Cytoprotective Activity under Oxidative Stress from Molecular Structure. Int. J. Mol. Sci. 24 (2023) 11349
6. R.Wawrzyniak, M. Guzowska, W. Wasiak, B. Jasiewicz, A. Bączkiewicz, K. Buczkowska, Seasonal Variability of Volatile Components in Calypogeia integristipula. Molecules 28 (2023) 7276
7. B.  Jasiewicz, K. Babijczuk, B. Warżajtis, U. Rychlewska, J. Starzyk, G. Cofta, L. Mrówczyńska, Indole Derivatives Bearing Imidazole, Benzothiazole-2-Thione or Benzoxazole-2-Thione Moieties — Synthesis, Structure and Evaluation of Their Cytoprotective, Antioxidant, Antibacterial and Fungicidal Activities. Molecules 28 (2023) 708
8. K. Babijczuk, B. Warżajtis, J. Starzyk, L. Mrówczyńska, B. Jasiewicz, U. Rychlewska, Synthesis, Structure and Biological Activity of Indole–Imidazole Complexes with ZnCl2: Can Coordination Enhance the Functionality of Bioactive Ligands? Molecules 28 (2023) 4132
9. A. Sierakowska, B. Jasiewicz, Ł. Piosik, L. Mrówczyńska, New C8‑substituted caffeine derivatives as promising antioxidants and cytoprotective agents in human erythrocytes Scientific Reports 13 (2023) 1785
10. N. Berdzik, B. Jasiewicz, K. Ostrowski, A. Sierakowska, M. Szlaużys, D. Nowak, L. Mrówczyńska, Novel gramine-based bioconjugates obtained by click chemistry as cytoprotective compounds and potent antibacterial and antifungal agents, Natural Product Research (2023): DOI: 10.1080/14786419.2023.2261139