ProfessorZdzisław Paryzek

Professor emeritus
  • 1970: Ph.D.
  • 1979: Habilitation
  • 1991: Professor

Functions:

  • Member of Polish Chemical Society
  • Supramolecular chemistry of steroids
  • Steroidal cyclobutanones: synthesis, reactivity and synthetic applications
  • Dimeric and macrocyclic derivatives of bile acids
  • Unusual ozonolyses of steroids
  • Molecular rearrangements of triterpenes

The most important publications:

  • Stereoelectronic and steric effects in the Baeyer–Villiger rearrangement of steroidal   α-chloro-cyclobutanones Z. Paryzek and H. Koenig Tetrahedron  (2012) 68, 9061–9067.
  • A new approach to steroid dimers and macrocycles by the reaction of 3-chlorocarbonyl derivatives of bile acids with O,O-, N,N-, and S,S-dinucleophiles Z. Paryzek, R. Joachimiak, M. Piasecka, T. Pospieszny Tetrahedron Letters  (2012), 53, 6212–6215.
  • A novel synthetic approach to (20R)- and (20S)-21-hydroxy steroids. Synthesis of a marine sterol 21-hydroxycholesterol H. Koenig, I. Skiera, K. Błaszczyk, Z. Paryzek Steroids  (2011) 76, 517–523.
  • Synthesis of novel amide-linked dimers of lithocholic acid R. Joachimiak, M. Piasecka, Z. Paryzek J.Chem. Res. (2008) 260-265
  • Ozonolysis of Cholesterol and other Δ5-steroids in the Presence of Alcohols; a Revised Mechanism and Hydroperoxide Structure of the Solvent-participated Product, Confirmed by X-ray Analysis" Z. Paryzek,  U. Rychlewska J. Chem. Soc., Perkin Trans. 2,  (1997) 2313-2318.